Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | FABP3 | P05413 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 2/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CCKAR | P32238 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | RPA1 | P27694 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210679 | 0.89 | BCL2 (0.43) | FABP3FABP4PTGS2CHRNA7BCL2 | |
| SCHEMBL6209746 | 0.87 | MDM2 (0.42) | FABP3FABP4PTGS2CHRNA7BCL2 | |
| SCHEMBL6208556 | 0.86 | FABP3 (0.40) | FFAR4FABP3FABP4PTGS2CHRNA7 | |
| SCHEMBL6208574 | 0.84 | MDM2 (0.41) | PTGS2CHRNA7BCL2MDM2MCL1 | |
| SCHEMBL6208572 | 0.83 | MALT1 (0.45) | PTGS2CHRNA7BCL2MDM2MCL1 | |
| SCHEMBL14505008 | 0.83 | MDM2 (0.43) | FABP3FABP4PTGS2CHRNA7BCL2 | |
| SCHEMBL14504991 | 0.80 | MDM2 (0.46) | FABP3FABP4PTGS2CHRNA7BCL2 | |
| SCHEMBL14505015 | 0.79 | PTGS2 (0.40) | FABP3FABP4PTGS2ALOX5 | |
| SCHEMBL5147693 | 0.78 | MALT1 (0.41) | FABP3FABP4PTGS2CHRNA7BCL2 | |
| SCHEMBL5148690 | 0.78 | FABP3 (0.41) | FABP3FABP4PTGS2BCL2MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567503-A1 | PYRAZOLE DERIVATIVES USEFUL AS COX-I INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004050632-A1 | PYRAZOLE DERIVATIVES USEFUL AS COX-I INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-06-17 | — | — | WO | disclosed |