Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 16/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212234 | 0.92 | CTSK (0.51) | CTSKCTSSCCR1CTSL | |
| SCHEMBL6213283 | 0.90 | CTSK (0.61) | CTSKCTSSCACNA1BCCR1CTSL | |
| SCHEMBL6214785 | 0.89 | CTSK (0.48) | CTSKCTSSCTSL | |
| SCHEMBL6213828 | 0.88 | CTSK (0.57) | CTSKCTSSCTSL | |
| SCHEMBL6211235 | 0.88 | CTSK (0.52) | CTSKCTSSCCR1CTSL | |
| SCHEMBL6210043 | 0.85 | CTSK (0.51) | CTSKCTSSCTSL | |
| SCHEMBL6210782 | 0.84 | CTSK (0.42) | CTSKCTSSCCR1CTSL | |
| SCHEMBL6210323 | 0.83 | CTSK (0.49) | CTSKCTSS | |
| SCHEMBL6210601 | 0.83 | CTSK (0.49) | CTSKCTSSCTSL | |
| SCHEMBL4037568 | 0.82 | CTSK (0.58) | CTSKCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546150-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | Amura Therapeutics Limited (GB) | 2005-06-29 | — | — | EP | disclosed |
| WO-2004007501-A1 | BIOLOGICALLY ACTIVE COMPOUNDS | AMURA THERAPEUTICS LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |