Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | DRD4 | P21917 | 6/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210413 | 1.00 | HTR1A (0.47) | HTR1ASLC6A4DRD4DRD2KCNH2 | |
| Hydrochloric Acid SCHEMBL6805660 | 0.98 | HTR1A (0.46) | HTR1ASLC6A4DRD4DRD2KCNH2 | |
| Hydrochloric Acid SCHEMBL6805651 | 0.98 | HTR1A (0.46) | HTR1ASLC6A4DRD4DRD2KCNH2 | |
| SCHEMBL5585000 | 0.92 | HTR1A (0.47) | HTR1ASLC6A4DRD4DRD2KCNH2 | |
| SCHEMBL5584998 | 0.92 | HTR1A (0.47) | HTR1ASLC6A4DRD4DRD2KCNH2 | |
| SCHEMBL5584364 | 0.91 | DRD4 (0.49) | HTR1ASLC6A4DRD4DRD2KCNH2 | |
| SCHEMBL5584367 | 0.91 | DRD4 (0.49) | HTR1ASLC6A4DRD4DRD2KCNH2 | |
| SCHEMBL5584898 | 0.91 | HTR1A (0.48) | HTR1ASLC6A4DRD4DRD2KCNH2 | |
| SCHEMBL5585164 | 0.91 | HTR1A (0.48) | HTR1ASLC6A4DRD4DRD2KCNH2 | |
| SCHEMBL14571523 | 0.89 | HTR1A (0.47) | HTR1ASLC6A4DRD4DRD2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7196199-B2 | Antiserotonine agents; antidepressants | MITSUBISHI PHARMA CORPORATION (JP) | 2007-03-27 | — | — | US | disclosed |
| US-7196199-B2 | Antiserotonine agents; antidepressants | MITSUBISHI PHARMA CORPORATION (JP) | 2007-03-27 | — | — | US | disclosed |
| EP-1188747-B1 | PHENOXYPROPYLAMINE COMPOUNDS | MITSUBISHI PHARMA CORP (JP) | 2005-09-07 | — | — | EP | disclosed |
| EP-1188747-A1 | PHENOXYPROPYLAMINE COMPOUNDS | Mitsubishi Pharma Corporation (JP) | 2002-03-20 | — | — | EP | disclosed |