Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PRKCI | P41743 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.44 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211504 | 0.92 | PDE5A (0.53) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL6214601 | 0.91 | KMT2A (0.62) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL6214705 | 0.90 | KMT2A (0.51) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL6211500 | 0.90 | KMT2A (0.51) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL6218405 | 0.89 | MAPT (0.46) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL6213742 | 0.87 | MAPT (0.44) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL6213558 | 0.86 | PRKCI (0.49) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL6214813 | 0.86 | HTT (0.46) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL6217377 | 0.85 | MAPT (0.45) | MAPTMEN1KMT2ASMN1; SMN2HTT | |
| SCHEMBL6796696 | 0.84 | PTPN12 (0.48) | MAPTMEN1KMT2ASMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351962-B1 | THIENOPYRIMIDINE | MERCK PATENT GMBH (DE) | 2005-03-16 | — | — | EP | disclosed |