Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212061 | 0.89 | MAPT (0.44) | PRKCIMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL6211504 | 0.89 | PDE5A (0.53) | PRKCIMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL6218405 | 0.88 | MAPT (0.46) | PRKCIMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL6211516 | 0.86 | MAPT (0.50) | PRKCIMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL6214705 | 0.85 | KMT2A (0.51) | PRKCIMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL6213742 | 0.85 | MAPT (0.44) | PRKCIMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL6214601 | 0.85 | KMT2A (0.62) | PRKCIMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL6211500 | 0.84 | KMT2A (0.51) | PRKCIMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL6215108 | 0.83 | PRKCI (0.48) | PRKCIMEN1KMT2AMAPTNPSR1 | |
| SCHEMBL6215341 | 0.83 | KMT2A (0.41) | PRKCIMEN1KMT2AMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351962-B1 | THIENOPYRIMIDINE | MERCK PATENT GMBH (DE) | 2005-03-16 | — | — | EP | disclosed |