Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 5/20 | 0.61 |
| ▸ | CASP3 | P42574 | 4/20 | 0.55 |
| ▸ | CTSL | P07711 | 3/20 | 0.52 |
| ▸ | CTSD | P07339 | 2/20 | 0.51 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | CASP9 | P55211 | 1/20 | 0.46 |
| ▸ | CASP4 | P49662 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL621234 | 1.00 | CTSB (0.61) | CTSBCASP3CTSLCTSDCASP7 | |
| SCHEMBL621232 | 1.00 | CTSB (0.61) | CTSBCASP3CTSLCTSDCASP7 | |
| SCHEMBL5133312 | 0.92 | CTSB (0.71) | CTSBCASP3CTSLCTSDCASP7 | |
| SCHEMBL14341580 | 0.92 | CTSB (0.71) | CTSBCASP3CTSLCTSDCASP7 | |
| SCHEMBL8537196 | 0.92 | CTSB (0.71) | CTSBCASP3CTSLCTSDCASP7 | |
| SCHEMBL23926088 | 0.92 | CTSB (0.71) | CTSBCASP3CTSLCTSDCASP7 | |
| SCHEMBL10084585 | 0.91 | CTSB (0.62) | CTSBCASP3CTSLCTSDCASP7 | |
| SCHEMBL10084583 | 0.91 | CTSB (0.62) | CTSBCASP3CTSLCTSDCASP7 | |
| SCHEMBL7806376 | 0.91 | CTSB (0.62) | CTSBCASP3CTSLCTSDCASP7 | |
| SCHEMBL7808000 | 0.91 | CTSB (0.62) | CTSBCASP3CTSLCTSDCASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021788-A2 | DIPEPTIDE CALPAIN INHIBITORS | BANYAN BIOMARKERS (US) | 2012-02-16 | — | — | WO | disclosed |