Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 13/20 | 0.67 |
| ▸ | CCR3 | P51677 | 13/20 | 0.67 |
| ▸ | CCR1 | P32246 | 6/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6214546 | 1.00 | HRH1 (0.67) | HRH1CCR3CCR1KCNH2HTR1A | |
| SCHEMBL6216373 | 1.00 | HRH1 (0.67) | HRH1CCR3CCR1KCNH2HTR1A | |
| Trifluoroacetic Acid SCHEMBL6211631 | 0.95 | HRH1 (0.61) | HRH1CCR3CCR1KCNH2 | |
| SCHEMBL6214133 | 0.95 | HRH1 (0.60) | HRH1CCR3CCR1KCNH2HTR1A | |
| SCHEMBL6210978 | 0.93 | HRH1 (0.67) | HRH1CCR3CCR1KCNH2HTR1A | |
| SCHEMBL6214542 | 0.92 | CCR1 (0.60) | HRH1CCR3CCR1KCNH2HTR1A | |
| SCHEMBL6216140 | 0.91 | HRH1 (0.65) | HRH1CCR3CCR1KCNH2 | |
| SCHEMBL6074255 | 0.91 | HRH1 (0.80) | HRH1CCR3CCR1KCNH2DRD2 | |
| SCHEMBL6212176 | 0.89 | HRH1 (0.60) | HRH1CCR3CCR1KCNH2HTR1A | |
| SCHEMBL6211635 | 0.87 | HRH1 (0.51) | HRH1CCR3CCR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263724-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2005-05-18 | — | — | EP | claimed |