Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 13/20 | 0.56 |
| ▸ | F10 | P00742 | 5/20 | 0.56 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.45 |
| ▸ | SCN4A | P35499 | 3/20 | 0.44 |
| ▸ | HRH2 | P25021 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6095270 | 1.00 | F2 (0.56) | F2F10SCN3ASCN9ASCN4A | |
| SCHEMBL6094164 | 0.88 | F2 (0.55) | F2F10SCN3ASCN9ASCN4A | |
| SCHEMBL6178965 | 0.86 | F2 (0.48) | F2F10SCN3ASCN9ASCN4A | |
| SCHEMBL6093799 | 0.80 | SCN4A (0.54) | F2F10SCN3ASCN4A | |
| SCHEMBL5795151 | 0.78 | SCN3A (0.67) | F2F10SCN3ASCN9ASCN4A | |
| SCHEMBL6094669 | 0.74 | SCN4A (0.48) | F2F10SCN3ASCN4A | |
| SCHEMBL6094815 | 0.73 | SCN4A (0.51) | F2F10SCN3ASCN4A | |
| SCHEMBL6977641 | 0.73 | F2 (0.53) | F2F10SCN3ASCN9ASCN4A | |
| SCHEMBL6094155 | 0.72 | CYP2D6 (0.47) | F2F10 | |
| SCHEMBL4420061 | 0.72 | F2 (1.00) | F2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1287018-B1 | THROMBIN INHIBITORS | LEK TOVARNA FARMACEVTSKIH (SI) | 2005-01-19 | — | — | EP | claimed |