Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN3A | Q9NY46 | 5/20 | 0.67 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.60 |
| ▸ | SCN4A | P35499 | 5/20 | 0.59 |
| ▸ | F2 | P00734 | 3/20 | 0.58 |
| ▸ | F10 | P00742 | 1/20 | 0.58 |
| ▸ | DRD3 | P35462 | 4/20 | 0.54 |
| ▸ | DRD2 | P14416 | 3/20 | 0.54 |
| ▸ | HRH2 | P25021 | 3/20 | 0.54 |
| ▸ | HRH1 | P35367 | 2/20 | 0.54 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8204692 | 0.82 | DRD3 (0.62) | SCN3ASCN9ASCN4AF2DRD3 | |
| SCHEMBL1031127 | 0.82 | DRD3 (0.62) | SCN3ASCN9ASCN4AF2DRD3 | |
| SCHEMBL1031126 | 0.82 | DRD3 (0.62) | SCN3ASCN9ASCN4AF2DRD3 | |
| SCHEMBL3025573 | 0.81 | SCN4A (0.62) | SCN3ASCN9ASCN4ADRD3DRD2 | |
| Bromide SCHEMBL4103965 | 0.81 | DRD3 (0.61) | SCN3ASCN9ASCN4AF2DRD3 | |
| SCHEMBL17165294 | 0.80 | DRD3 (0.60) | SCN3ASCN9ASCN4AF2F10 | |
| SCHEMBL7321908 | 0.79 | MAPT (0.70) | MAPTLMNAPOLB | |
| Hydrochloric Acid SCHEMBL7316817 | 0.78 | ADRA2A (0.66) | SCN3ASCN9ASCN4ADRD3DRD2 | |
| SCHEMBL6214732 | 0.78 | F2 (0.56) | SCN3ASCN9ASCN4AF2F10 | |
| SCHEMBL3435133 | 0.77 | SCN4A (0.61) | SCN3ASCN9ASCN4ADRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012277-A2 | BIOCATALYTIC PROCESS FOR PREPARING ENANTIOMERICALLY ENRICHED PRAMIPEXOLE | AMR TECHNOLOGY, INC. (US) | 2006-02-02 | — | — | WO | disclosed |