SCHEMBL621480 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	CAPN1	P07384	10/20	0.67

▸	MEN1	O00255	2/20	0.40

▸	KMT2A	Q03164	2/20	0.40

▸	LMNA	P02545	1/20	0.40

▸	PSMB5	P28074	1/20	0.39

▸	CYP2C19	P33261	1/20	0.39

▸	SMN1; SMN2	Q16637	1/20	0.39

▸	ATM	Q13315	1/20	0.38

▸	HRH1	P35367	1/20	0.38

▸	CASP3	P42574	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL621481	1.00	CAPN1 (0.67)	CAPN1MEN1KMT2ALMNAPSMB5
SCHEMBL622532	0.82	CAPN1 (0.55)	CAPN1HRH1
SCHEMBL623798	0.81	CAPN1 (0.54)	CAPN1HRH1
SCHEMBL356129	0.80	CAPN1 (1.00)	CAPN1
SCHEMBL3837585	0.80	CAPN1 (1.00)	CAPN1
SCHEMBL19553159	0.80	CAPN1 (1.00)	CAPN1
SCHEMBL3838718	0.80	CAPN1 (1.00)	CAPN1
SCHEMBL20873431	0.80	CAPN1 (1.00)	CAPN1
SCHEMBL20873408	0.80	CAPN1 (1.00)	CAPN1
SCHEMBL3838115	0.80	CAPN1 (1.00)	CAPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012021788-A2	DIPEPTIDE CALPAIN INHIBITORS	BANYAN BIOMARKERS (US)	2012-02-16	—	—	WO	disclosed
WO-2012021788-A2	DIPEPTIDE CALPAIN INHIBITORS	BANYAN BIOMARKERS (US)	2012-02-16	—	—	WO	disclosed