Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.48 |
| ▸ | RAB9A | P51151 | 8/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MLNR | O43193 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.47 |
| ▸ | RELA | Q04206 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5958476 | 1.00 | MEN1 (0.49) | MEN1LMNAHPGDTSHRHTT | |
| Ethoxycarbonyl Group SCHEMBL27613617 | 0.78 | NPC1 (0.47) | MEN1LMNAHPGDTSHRHTT | |
| SCHEMBL5958573 | 0.78 | NPC1 (0.45) | MEN1LMNAHPGDTSHRHTT | |
| SCHEMBL6215718 | 0.78 | NPC1 (0.45) | MEN1LMNAHPGDTSHRHTT | |
| SCHEMBL28757265 | 0.74 | NPC1 (0.49) | MEN1LMNAHPGDTSHRHTT | |
| Hydrochloric Acid SCHEMBL5958619 | 0.73 | KCNH2 (0.58) | MEN1LMNAHPGDTSHRHTT | |
| SCHEMBL1544106 | 0.72 | MEN1 (0.64) | MEN1LMNAHPGDTSHRHTT | |
| SCHEMBL27613555 | 0.72 | ALDH1A1 (0.40) | LMNATSHRKMT2ANPC1RAB9A | |
| SCHEMBL6211139 | 0.71 | NPC1 (0.46) | TSHRNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL5958356 | 0.71 | NPC1 (0.46) | TSHRNPC1RAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1536790-A2 | OXADIAZOLES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5 | AstraZeneca AB (SE) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004014370-A2 | OXADIAZOLES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5 | ASTRAZENECA AB (SE) | 2004-02-19 | — | — | WO | disclosed |