Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 20/20 | 0.60 |
| ▸ | CCR3 | P51677 | 20/20 | 0.60 |
| ▸ | CCR1 | P32246 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 10/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6074255 | 0.86 | HRH1 (0.80) | HRH1CCR3CCR1KCNH2 | |
| SCHEMBL3282846 | 0.84 | HRH1 (0.73) | HRH1CCR3CCR1KCNH2 | |
| Hydrochloric Acid SCHEMBL7494378 | 0.81 | HRH1 (0.72) | HRH1CCR3CCR1KCNH2 | |
| SCHEMBL6212138 | 0.81 | HRH1 (0.72) | HRH1CCR3CCR1KCNH2 | |
| Hydrochloric Acid SCHEMBL6215275 | 0.80 | HRH1 (0.71) | HRH1CCR3CCR1KCNH2 | |
| SCHEMBL6216475 | 0.80 | HRH1 (0.69) | HRH1CCR3CCR1KCNH2 | |
| SCHEMBL6210512 | 0.80 | HRH1 (0.66) | HRH1CCR3CCR1KCNH2 | |
| SCHEMBL6216140 | 0.79 | HRH1 (0.65) | HRH1CCR3CCR1KCNH2 | |
| SCHEMBL6211670 | 0.79 | HRH1 (0.65) | HRH1CCR3CCR1KCNH2 | |
| SCHEMBL3294155 | 0.79 | HRH1 (0.63) | HRH1CCR3CCR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1263724-B1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2005-05-18 | — | — | EP | claimed |