Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 8/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | FSHR | P23945 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217958 | 0.82 | CHRM4 (0.60) | LHCGRTSHRFSHRCHRM4ALDH1A1 | |
| SCHEMBL6217802 | 0.80 | LHCGR (0.58) | LHCGRTSHRFSHRCHRM4KDM4E | |
| SCHEMBL6220425 | 0.79 | LHCGR (0.55) | LHCGRTSHRFSHRCHRM4CNR1 | |
| SCHEMBL6215311 | 0.78 | LHCGR (0.61) | LHCGRTSHRFSHRKDM4EALDH1A1 | |
| SCHEMBL6216183 | 0.78 | LHCGR (0.54) | LHCGRTSHRFSHRCHRM4KDM4E | |
| SCHEMBL6216455 | 0.78 | LHCGR (0.59) | LHCGRTSHRFSHRKDM4EALDH1A1 | |
| SCHEMBL6217403 | 0.77 | LHCGR (0.60) | LHCGRTSHRFSHRCHRM4KDM4E | |
| SCHEMBL6216753 | 0.77 | LHCGR (0.55) | LHCGRTSHRFSHRCHRM4CNR1 | |
| SCHEMBL6217357 | 0.77 | LHCGR (0.55) | LHCGRTSHRFSHRCHRM4 | |
| SCHEMBL6214860 | 0.77 | LHCGR (0.56) | LHCGRTSHRFSHRCHRM4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171443-B1 | BICYCLIC HETEROAROMATIC COMPOUNDS USEFUL AS LH AGONISTS | AKZO NOBEL NV (NL) | 2005-07-13 | — | — | EP | disclosed |
| US-6841553-B2 | Bicyclic heteroaromatic compounds useful as LH agonists | AKZO NOBEL N.V. (NL) | 2005-01-11 | — | — | US | disclosed |
| US-20030212081-A1 | Bicyclic heteroaromatic compounds useful as LH agonists | MERCK SHARP & DOHME B.V. (NL) | 2003-11-13 | — | — | US | disclosed |
| US-6569863-B1 | Luteinizing hormone (LH) agonists for controlling fertility | AKZO NOBEL NV (NL) | 2003-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212081-A1 | Bicyclic heteroaromatic compounds useful as LH agonists | LHCGR, GNRHR, FSHR | LHCGR 1/4885TSHR 176/4885FSHR 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.