Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217114 | 0.87 | THRB (0.67) | THRBTHRA | |
| SCHEMBL6217449 | 0.87 | THRB (0.74) | THRBTHRA | |
| SCHEMBL6216234 | 0.86 | THRB (0.70) | THRBTHRA | |
| SCHEMBL6217453 | 0.85 | THRB (0.71) | THRBTHRA | |
| SCHEMBL4314269 | 0.85 | THRB (1.00) | THRBTHRA | |
| SCHEMBL6216771 | 0.84 | THRB (0.70) | THRBTHRA | |
| SCHEMBL6213769 | 0.81 | THRB (0.64) | THRBTHRA | |
| SCHEMBL6212340 | 0.80 | THRB (0.98) | THRBTHRA | |
| SCHEMBL1642033 | 0.80 | THRB (1.00) | THRBTHRA | |
| SCHEMBL6217508 | 0.80 | THRB (0.72) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6930107-B2 | 6-azauracil derivatives as thyroid receptor ligands | PFIZER INC. (US) | 2005-08-16 | — | — | US | disclosed |
| EP-1088819-B1 | 6-azauracil derivatives as thyroid receptor ligands | PFIZER PROD INC (US) | 2005-06-15 | — | — | EP | disclosed |
| US-6787652-B1 | LOWERING LIPIDS AND SERUM CHOLESTEROL WITHOUT GENERATING ADVERSE CARDIAC EFFECTS; 4,5-DIHYDRO-3,5-DIOXO-1,2,4-TRIAZINE DERIVATIVES | PFIZER, INC. | 2004-09-07 | — | — | US | disclosed |
| EP-1088819-A2 | 6-azauracil derivatives as thyroid receptor ligands | Pfizer Products Inc. (US) | 2001-04-04 | — | — | EP | disclosed |