SCHEMBL6216634

SCHEMBL6216634

CC(=O)NCCc1cccc2ccc(OCCCOc3ccc(-c4ccc(C(=O)O)cc4)cc3)cc12

nearest known ligand 0.96

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 20/20 0.96
MTNR1B P49286 17/20 0.96

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5344020 0.98 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL5350648 0.97 MTNR1A (0.94) MTNR1AMTNR1B
SCHEMBL5346224 0.91 MTNR1A (0.96) MTNR1AMTNR1B
SCHEMBL5340272 0.91 MTNR1A (0.86) MTNR1AMTNR1B
SCHEMBL7017361 0.89 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL5346427 0.89 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL5346035 0.88 MTNR1A (0.94) MTNR1AMTNR1B
SCHEMBL5349369 0.87 MTNR1A (0.75) MTNR1AMTNR1B
SCHEMBL7015269 0.87 MTNR1A (1.00) MTNR1AMTNR1B
SCHEMBL6213956 0.86 MTNR1A (0.76) MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1317413-B1 SUBSTITUTED BIPHENYL DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME SERVIER LAB (FR) 2005-08-24 EP disclosed
EP-1317413-A1 SUBSTITUTED BIPHENYL DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Les Laboratoires Servier (FR) 2003-06-11 EP disclosed
WO-2002022555-A1 SUBSTITUTED BIPHENYL DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME LES LABORATOIRES SERVIER (FR) 2002-03-21 WO disclosed