Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | KCNQ3 | O43525 | 2/20 | 0.46 |
| ▸ | KCNQ2 | O43526 | 2/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778641 | 1.00 | FFAR1 (0.55) | FFAR1SLC6A2SLC6A4CYP1A2CYP2C19 | |
| SCHEMBL13545677 | 0.86 | SLC6A2 (0.47) | FFAR1SLC6A2SLC6A4CYP1A2CYP2C19 | |
| SCHEMBL901089 | 0.84 | SLC6A2 (0.48) | FFAR1SLC6A2SLC6A4CYP1A2CYP2C19 | |
| SCHEMBL838634 | 0.83 | KCNQ3 (0.56) | FFAR1SLC6A2SLC6A4CYP2C19ALDH1A1 | |
| SCHEMBL22492058 | 0.83 | KCNQ3 (0.56) | FFAR1SLC6A2SLC6A4CYP2C19ALDH1A1 | |
| SCHEMBL22492062 | 0.83 | KCNQ3 (0.56) | FFAR1SLC6A2SLC6A4CYP2C19ALDH1A1 | |
| SCHEMBL12354198 | 0.83 | KCNQ3 (0.56) | FFAR1SLC6A2SLC6A4CYP2C19ALDH1A1 | |
| SCHEMBL14921525 | 0.82 | SMN1; SMN2 (0.51) | SLC6A2SLC6A4ALDH1A1KCNQ3KCNQ2 | |
| SCHEMBL5251428 | 0.82 | SLC6A2 (0.47) | FFAR1SLC6A2SLC6A4CYP1A2CYP2C19 | |
| SCHEMBL14921526 | 0.82 | SMN1; SMN2 (0.51) | SLC6A2SLC6A4ALDH1A1KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1187812-B1 | SUBSTITUTED PHENYLCYCLOHEXANE CARBOXYLIC ACID AMIDES AND THEIR USE AS ADENOSINE UPTAKE INHIBITORS | BAYER HEALTHCARE AG (DE) | 2005-09-07 | — | — | EP | disclosed |
| US-20040186106-A1 | Substituted phenylcyclohexane carboxylic acid amides that have an adenosine uptake inhibiting effect | BAYER HEALTHCARE AG (DE) | 2004-09-23 | — | — | US | disclosed |
| US-6716849-B1 | ISCHEMIC BRAIN DISORDERS; NEUROPROTECTANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-04-06 | — | — | US | disclosed |
| US-5834481-A | HYPOTENSIVE AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-10 | — | — | US | disclosed |
| US-5708003-A | TREATING ARTERIAL HYPERTENSION AND ATHEROSCLEROSIS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | disclosed |
| US-5508299-A | ANGIOTENSIN CONVERTING ENZYME INHIBITOR, ARTERIAL HYPOTENSIVE AGENT; CARDIOVASCULAR DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |
| US-5478836-A | Treaing hypertension, atheroschlerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5395840-A | Hypotensive agents; atherosclerosis | BAYER AKTIENGESELLSCHAFT (DE) | 1995-03-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040186106-A1 | Substituted phenylcyclohexane carboxylic acid amides that have an adenosine uptake inhibiting effect | ADORA1, ADORA2A, ADORA3 | FFAR1 252/4885SLC6A2 49/4885SLC6A4 120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.