Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | FADS1 | O60427 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4486769 | 0.78 | CYP3A4 (0.39) | MAOBL3MBTL1MAPTNPC1MEN1 | |
| Hydrochloric Acid SCHEMBL6216834 | 0.77 | CYP3A4 (0.34) | L3MBTL1MAPTMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4515785 | 0.74 | F2 (0.32) | MAPTALDH1A1CYP3A4TP53MAPK1 | |
| SCHEMBL4341830 | 0.74 | BCHE (0.38) | HSD17B3L3MBTL1MAPTNPC1MEN1 | |
| Hydrochloric Acid SCHEMBL4509026 | 0.74 | CYP3A4 (0.31) | MAPTKMT2AALDH1A1CYP3A4TP53 | |
| SCHEMBL4354365 | 0.72 | BCHE (0.40) | HSD17B3L3MBTL1MAPTNPC1MEN1 | |
| SCHEMBL4522630 | 0.69 | CYP3A4 (0.32) | L3MBTL1MAPTALDH1A1CYP3A4TP53 | |
| SCHEMBL10674390 | 0.65 | LMNA (0.43) | USP2L3MBTL1MAPTNPC1MEN1 | |
| SCHEMBL4345823 | 0.63 | CYP3A4 (0.42) | HSD17B3L3MBTL1MAPTNPC1MEN1 | |
| SCHEMBL5837144 | 0.62 | BRD4 (0.68) | CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496053-A1 | KAPPA-OPIOID RECEPTOR AGONIST COMPRISING 2-PHENYLBENZOTHIAZOLINE DERIVATIVE | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2005-01-12 | — | — | EP | disclosed |