SCHEMBL6217372

SCHEMBL6217372

O=C(Nc1ccc2[nH]ncc2c1)NC1CCCCC1CN1CCC(Cc2ccc(F)cc2)CC1

nearest known ligand 0.84

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 20/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6217369 1.00 CCR3 (0.84) CCR3
SCHEMBL18840967 0.92 CCR3 (1.00) CCR3
SCHEMBL18841163 0.92 CCR3 (1.00) CCR3
SCHEMBL3881547 0.85 CCR3 (0.73) CCR3
SCHEMBL3881302 0.82 CCR3 (0.67) CCR3
SCHEMBL6217193 0.81 CCR3 (0.71) CCR3
SCHEMBL6217202 0.81 CCR3 (0.71) CCR3
SCHEMBL4578305 0.81 CHRNB2 (0.69) CCR3
SCHEMBL6217198 0.81 CCR3 (0.71) CCR3
SCHEMBL6217391 0.79 CCR3 (1.00) CCR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1161240-B1 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY BRISTOL MYERS SQUIBB PHARMA CO (US) 2005-08-17 EP claimed
US-20030114489-A1 N-ureidoalkyl-piperidines as modulators of chemokine receptor activity KO SOO S (US) 2003-06-19 US claimed
US-6444686-B1 FOR THE PREVENTION OF ASTHMA AND OTHER ALLERGIC DISEASES. BRSITOL-MYERS SQUIBB PHARMA COMPANY 2002-09-03 US claimed
EP-1161240-A4 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY DU PONT PHARM CO (US) 2002-04-03 EP claimed
EP-1161240-A1 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY Du Pont Pharmaceuticals Company (US) 2001-12-12 EP claimed
WO-2000035452-A1 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY DU PONT PHARMACEUTICALS COMPANY (US) 2000-06-22 WO claimed
EP-1161240-B1 N-UREIDOALKYL-PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY BRISTOL MYERS SQUIBB PHARMA CO (US) 2005-08-17 EP disclosed
US-6897234-B2 N-ureidoalkyl-piperidines as modulators of chemokine receptor activity BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2005-05-24 US disclosed
US-20050096325-A1 N-ureidoalkyl-piperidines as modulators of chemokine receptor activity KO SOO S (US) 2005-05-05 US disclosed
US-20030114489-A1 N-ureidoalkyl-piperidines as modulators of chemokine receptor activity KO SOO S (US) 2003-06-19 US disclosed
US-6444686-B1 FOR THE PREVENTION OF ASTHMA AND OTHER ALLERGIC DISEASES. BRSITOL-MYERS SQUIBB PHARMA COMPANY 2002-09-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050096325-A1 N-ureidoalkyl-piperidines as modulators of chemokine receptor activity CCR3, CCR1, ACKR3 CCR3 1/4885
US-20030114489-A1 N-ureidoalkyl-piperidines as modulators of chemokine receptor activity CCR3, CCR1, CCR10 CCR3 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.