SCHEMBL6217396

SCHEMBL6217396

CC(=O)CNc1ccc(C(=O)Nc2ccccc2C(=O)Nc2ccc(Cl)cn2)cc1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2439110 0.92 F10 (0.72) F10
SCHEMBL6219022 0.90 F10 (0.70) F10
SCHEMBL6215501 0.87 F10 (0.70) F10
SCHEMBL2436713 0.86 F10 (0.72) F10
SCHEMBL6218916 0.85 F10 (0.71) F10
SCHEMBL5789507 0.84 F10 (0.61) F10
SCHEMBL6217486 0.82 F10 (0.63) F10
SCHEMBL2431813 0.82 F10 (0.72) F10
SCHEMBL6108304 0.82 F10 (0.72) F10
SCHEMBL6807574 0.82 F10 (0.72) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1465892-A4 GLYCINAMIDES AS FACTOR XA INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2005-11-30 EP claimed
EP-1465892-A1 GLYCINAMIDES AS FACTOR XA INHIBITORS Bristol-Myers Squibb Company (US) 2004-10-13 EP claimed
WO-2003048158-A1 GLYCINAMIDES AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-06-12 WO claimed
EP-1465892-A4 GLYCINAMIDES AS FACTOR XA INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2005-11-30 EP disclosed
EP-1465892-A1 GLYCINAMIDES AS FACTOR XA INHIBITORS Bristol-Myers Squibb Company (US) 2004-10-13 EP disclosed
WO-2003048081-A2 GLYCINAMIDES AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-06-12 WO disclosed
WO-2003048158-A1 GLYCINAMIDES AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-06-12 WO disclosed