SCHEMBL6217486

SCHEMBL6217486

CCCCN(C)CC(=O)CNc1ccc(C(=O)Nc2ccccc2C(=O)Nc2ccc(Cl)cn2)cc1

nearest known ligand 0.63

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.63
KLKB1 P03952 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6218521 0.90 F10 (0.63) F10KLKB1
SCHEMBL6217674 0.89 F10 (0.63) F10KLKB1
SCHEMBL6108259 0.85 F10 (0.65) F10
SCHEMBL6217396 0.82 F10 (0.68) F10
SCHEMBL2439110 0.81 F10 (0.72) F10
SCHEMBL2436713 0.77 F10 (0.72) F10
SCHEMBL6214943 0.77 F10 (0.72) F10KLKB1
SCHEMBL14285962 0.77 F10 (0.76) F10
SCHEMBL10178331 0.77 F10 (1.00) F10
SCHEMBL6107845 0.76 F10 (0.68) F10KLKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003048081-A2 GLYCINAMIDES AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-06-12 WO claimed
EP-1465892-A4 GLYCINAMIDES AS FACTOR XA INHIBITORS BRISTOL MYERS SQUIBB CO (US) 2005-11-30 EP disclosed
EP-1465892-A1 GLYCINAMIDES AS FACTOR XA INHIBITORS Bristol-Myers Squibb Company (US) 2004-10-13 EP disclosed
WO-2003048158-A1 GLYCINAMIDES AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2003-06-12 WO disclosed