Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6220252 | 0.95 | ANPEP (0.32) | ENPP2MMP2ANPEP | |
| SCHEMBL6218683 | 0.89 | ITGB2 (0.35) | — | |
| SCHEMBL6201490 | 0.87 | ITGB2 (0.37) | — | |
| SCHEMBL6220383 | 0.85 | KDM4E (0.32) | — | |
| SCHEMBL6218987 | 0.85 | ITGB2 (0.36) | ENPP2MMP2ANPEP | |
| SCHEMBL6219913 | 0.84 | GPR183 (0.37) | ENPP2 | |
| SCHEMBL6197037 | 0.82 | ITGB2 (0.38) | — | |
| SCHEMBL6222372 | 0.79 | PARP14 (0.38) | ENPP2GPR119PARP14 | |
| SCHEMBL6220061 | 0.79 | ENPP2 (0.36) | ENPP2 | |
| SCHEMBL6217553 | 0.79 | ENPP2 (0.34) | ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140814-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2005-05-25 | — | — | EP | claimed |