SCHEMBL6217993

SCHEMBL6217993

CC(=S)NCC1CN(c2ccc(ON3CCCCC3)c(F)c2)C(=O)O1

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.55
MAOB P27338 6/20 0.55
PTGS1 P23219 2/20 0.55
SDHA P31040 2/20 0.55
LMNA P02545 1/20 0.55
CALML3 P27482 1/20 0.55
F10 P00742 8/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5724702 0.92 MAOA (0.64) MAOAMAOBPTGS1SDHALMNA
SCHEMBL13159169 0.80 MAOB (0.66) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6045165 0.79 MAOB (0.85) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6045171 0.79 MAOB (0.85) MAOAMAOBPTGS1SDHALMNA
SCHEMBL21969133 0.78 F10 (0.68) MAOAMAOBPTGS1SDHALMNA
SCHEMBL5422798 0.78 F10 (0.69) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6160301 0.78 MAOB (0.85) MAOAMAOBPTGS1SDHALMNA
SCHEMBL5422795 0.78 F10 (0.69) MAOAMAOBPTGS1SDHALMNA
SCHEMBL6040542 0.78 MAOB (0.85) MAOAMAOBPTGS1SDHALMNA
SCHEMBL5404129 0.78 MAOB (0.66) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1594852-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES, LTD. (IN) 2005-11-16 EP disclosed
WO-2004069816-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2004-08-19 WO disclosed