SCHEMBL621820

SCHEMBL621820

COc1ccc(Br)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18032751 0.86 PDGFRB (0.38)
SCHEMBL20176230 0.84 APP (0.38)
SCHEMBL5157282 0.80
SCHEMBL434813 0.70
SCHEMBL14871942 0.70 APP (0.46)
SCHEMBL147222 0.69
SCHEMBL131605 0.69
SCHEMBL5645611 0.69 APP (0.50)
SCHEMBL4094325 0.69 CES2 (0.41)
SCHEMBL29221597 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120005149-A Polyarylene amine hole transport material and perovskite solar cell prepared from same 中国长江三峡集团有限公司 2025-05-16 CN claimed
CN-119638984-A Polyaramid hole transport material, synthesis method thereof and perovskite solar cell 浙江大学 2025-03-18 CN claimed
US-12630521-B2 Arylamides and methods of use thereof GENZYME CORPORATION (US) 2026-05-19 US disclosed
CN-120005149-A Polyarylene amine hole transport material and perovskite solar cell prepared from same 中国长江三峡集团有限公司 2025-05-16 CN disclosed
CN-119638984-A Polyaramid hole transport material, synthesis method thereof and perovskite solar cell 浙江大学 2025-03-18 CN disclosed
CN-116283897-A Compound and application of compound in solar cell 西安隆基乐叶光伏科技有限公司 2023-06-23 CN disclosed
WO-2023109035-A1 COMPOUND AND USE THEREOF IN SOLAR CELL 西安隆基乐叶光伏科技有限公司 2023-06-22 WO disclosed
US-20230147360-A1 ARYLAMIDES AND METHODS OF USE THEREOF GENZYME CORPORATION 2023-05-11 US disclosed
US-20230147360-A1 ARYLAMIDES AND METHODS OF USE THEREOF GENZYME CORPORATION 2023-05-11 US disclosed
US-20230147360-A1 ARYLAMIDES AND METHODS OF USE THEREOF GENZYME CORPORATION 2023-05-11 US disclosed
CN-114502564-A EGFR inhibitor, composition and preparation method thereof 贝达药业股份有限公司 2022-05-13 CN disclosed
US-7084170-B2 Thiophene-amd thiazolesulfonamides as antineoplastic agents ELI LILLY AND COMPANY (US) 2006-08-01 US disclosed
US-RE36256-E ADMINISTERING ARYL-SUBSTITUTED QUINOXALINE DERIVATIVES AS ANTIPROLIFERATIVE, ANTICARCINOGENIC AND ANTITUMOR AGENTS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1999-07-20 US disclosed
US-5795889-A INHIBITING CELL GROWTH WITH ENZYME INHIBITORS FOR SKIN DISORDERS RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-08-18 US disclosed
CN-1190395-A Substituted (sulfonic, sulfinic, sulfonamido or sulfonamido) N- [ aminoiminomethyl) phenylalkyl ] -azaheterocyclic amide compounds RHONE POULENC RORER PHARMA (US) 1998-08-12 CN disclosed
US-5656643-A QUINOLIN PYRIDINE DERIVATIVES; USEFUL FOR TREATING CANCER, LEKEMIA, PSORIASIS, INFLAMMATORY DISODERS, BONE DISORDERS, ATHEROSCLEROSIS AND RESTENOSIS; CONTROLLS CELLULAR REPRODUCTION RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1997-08-12 US disclosed
US-5646153-A INHIBITING ABNORMAL CELL PROLIFERATION RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1997-07-08 US disclosed
US-5480883-A Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1996-01-02 US disclosed
US-5409930-A Inhibits abnoramal cell proliferation; dimethoxyquinoline/ dimethylquinoline/ quinolineoxide/ and quinoxaline derivatives RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1995-04-25 US disclosed
WO-1992020642-A1 BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) 1992-11-26 WO disclosed