Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | UGCG | Q16739 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6216452 | 0.87 | CHRM3 (0.42) | CHRM3 | |
| SCHEMBL6667667 | 0.85 | ACHE (0.46) | CHRM3 | |
| SCHEMBL6219038 | 0.85 | NR1I2 (0.41) | NR1I2UGCGALDH1A1MCL1MAPK1 | |
| SCHEMBL6218160 | 0.83 | CHRM3 (0.40) | CHRM3 | |
| SCHEMBL6216460 | 0.81 | CHRM3 (0.40) | CHRM3 | |
| SCHEMBL6217139 | 0.81 | CHRM3 (0.42) | CHRM3 | |
| SCHEMBL5779881 | 0.79 | NR1I2 (0.52) | NR1I2UGCGALDH1A1MCL1MAPK1 | |
| SCHEMBL4309214 | 0.79 | CHRM3 (0.43) | NR1I2UGCGCHRM3ALDH1A1MCL1 | |
| SCHEMBL5781800 | 0.77 | HDAC1 (0.42) | NR1I2UGCGALDH1A1MCL1MAPK1 | |
| SCHEMBL5782997 | 0.76 | PARP1 (0.41) | NR1I2UGCGALDH1A1MCL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1414817-B1 | substituted isoindoles and the use thereof | BAYER HEALTHCARE AG (DE) | 2005-04-06 | — | — | EP | disclosed |