Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.63 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217674 | 0.92 | F10 (0.63) | F10KLKB1KCNH2 | |
| SCHEMBL6217486 | 0.90 | F10 (0.63) | F10KLKB1 | |
| SCHEMBL6106678 | 0.86 | F10 (0.69) | F10KLKB1KCNH2 | |
| SCHEMBL6215501 | 0.83 | F10 (0.70) | F10KLKB1KCNH2 | |
| SCHEMBL2431132 | 0.82 | F10 (0.73) | F10KLKB1KCNH2 | |
| SCHEMBL6105601 | 0.82 | F10 (0.70) | F10KLKB1KCNH2 | |
| SCHEMBL6214943 | 0.80 | F10 (0.72) | F10KLKB1KCNH2 | |
| SCHEMBL2433780 | 0.78 | F10 (0.73) | F10KLKB1KCNH2 | |
| SCHEMBL799840 | 0.78 | F10 (1.00) | F10KCNH2 | |
| SCHEMBL6108061 | 0.78 | F10 (0.77) | F10KLKB1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465892-A4 | GLYCINAMIDES AS FACTOR XA INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2005-11-30 | — | — | EP | claimed |
| EP-1465892-A1 | GLYCINAMIDES AS FACTOR XA INHIBITORS | Bristol-Myers Squibb Company (US) | 2004-10-13 | — | — | EP | claimed |
| WO-2003048158-A1 | GLYCINAMIDES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-06-12 | — | — | WO | claimed |
| WO-2003048081-A2 | GLYCINAMIDES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-06-12 | — | — | WO | claimed |
| WO-2003048081-A2 | GLYCINAMIDES AS FACTOR XA INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-06-12 | — | — | WO | disclosed |