Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4815086 | 0.87 | CHEK1 (1.00) | CHEK1PDGFRB | |
| SCHEMBL6961118 | 0.86 | CHEK1 (0.80) | CHEK1PDGFRB | |
| SCHEMBL4809966 | 0.85 | CHEK1 (1.00) | CHEK1PDGFRB | |
| SCHEMBL11864274 | 0.85 | CHEK1 (0.78) | CHEK1PDGFRB | |
| SCHEMBL4810301 | 0.85 | CHEK1 (1.00) | CHEK1PDGFRB | |
| SCHEMBL4812739 | 0.85 | CHEK1 (1.00) | CHEK1PDGFRB | |
| SCHEMBL4816112 | 0.84 | CHEK1 (0.81) | CHEK1PDGFRB | |
| SCHEMBL4813556 | 0.84 | CHEK1 (1.00) | CHEK1PDGFRB | |
| SCHEMBL4813974 | 0.82 | CHEK1 (1.00) | CHEK1PDGFRB | |
| SCHEMBL4814094 | 0.81 | CHEK1 (1.00) | CHEK1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603885-A1 | FUSED TRI AND TETRA-CYCLIC PYRAZOLE KINASE INHIBITORS | Abbott Laboratories (US) | 2005-12-14 | — | — | EP | claimed |
| WO-2004080973-A1 | FUSED TRI AND TETRA-CYCLIC PYRAZOLE KINASE INHIBITORS | ABBOTT LABORATORIES (US) | 2004-09-23 | — | — | WO | claimed |