Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GPR6 | P46095 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218839 | 0.91 | PTGDR (0.42) | PTGDRIKBKBUTS2RPDE4APDE4B | |
| SCHEMBL6104086 | 0.91 | PTGDR (0.45) | PTGDRIKBKBUTS2RALDH1A1RORC | |
| SCHEMBL6247991 | 0.84 | PTGDR (0.38) | PTGDRIKBKBPDE4APDE4BPDE4C | |
| SCHEMBL6247984 | 0.84 | PTGDR (0.38) | PTGDRIKBKBPDE4APDE4BPDE4C | |
| SCHEMBL6247985 | 0.84 | PTGDR (0.38) | PTGDRIKBKBPDE4APDE4BPDE4C | |
| SCHEMBL6221153 | 0.84 | IKBKB (0.44) | PTGDRIKBKBALDH1A1RORCL3MBTL1 | |
| SCHEMBL6220281 | 0.83 | EPHX2 (0.41) | PTGDRIKBKBUTS2RPDE4APDE4B | |
| SCHEMBL6362089 | 0.80 | PTGDR (0.41) | PTGDRIKBKBUTS2RPDE4APDE4B | |
| SCHEMBL6245804 | 0.77 | PTGDR (0.44) | PTGDRIKBKBUTS2RALDH1A1POLB | |
| SCHEMBL6104724 | 0.77 | PTGDR (0.44) | PTGDRIKBKBUTS2RALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539159-A1 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | Astrazeneca AB (SE) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004006926-A1 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-01-22 | — | — | WO | disclosed |
| WO-2004006926-A1 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-01-22 | — | — | WO | disclosed |