Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | IKBKB | O14920 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GPR6 | P46095 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218839 | 0.86 | PTGDR (0.42) | PTGDRIKBKBUTS2RPDE4APDE4B | |
| SCHEMBL6218902 | 0.80 | PTGDR (0.42) | PTGDRIKBKBUTS2RPDE4APDE4B | |
| SCHEMBL6104086 | 0.80 | PTGDR (0.45) | PTGDRIKBKBUTS2RSMN1; SMN2GPR6 | |
| SCHEMBL6362091 | 0.78 | PTGDR (0.43) | PTGDRIKBKBSMN1; SMN2GPR6 | |
| SCHEMBL6218845 | 0.75 | GPR6 (0.36) | IKBKBCYP2D6L3MBTL1GPR6ALDH1A1 | |
| SCHEMBL6103913 | 0.73 | TDO2 (0.47) | IKBKBPDE4BCYP2D6L3MBTL1GPR6 | |
| SCHEMBL6245804 | 0.72 | PTGDR (0.44) | PTGDRIKBKBUTS2RALDH1A1 | |
| SCHEMBL6104724 | 0.72 | PTGDR (0.44) | PTGDRIKBKBUTS2RALDH1A1 | |
| SCHEMBL6245802 | 0.72 | PTGDR (0.44) | PTGDRIKBKBUTS2RALDH1A1 | |
| SCHEMBL6103514 | 0.72 | PTGDR (0.41) | PTGDRIKBKBUTS2RSMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539159-A1 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | Astrazeneca AB (SE) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004006926-A1 | SULPHONYLPIPERIDINE DERIVATIVES CONTAINING AN ARYL OR HETEROARYL GROUP FOR USE AS MATRIX METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2004-01-22 | — | — | WO | disclosed |