Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6253513 | 0.91 | PTPN1 (0.43) | PPARGGAAPTPN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL6250714 | 0.90 | GAA (0.35) | GAAPTPN1SMN1; SMN2ALDH1A1PDE10A | |
| SCHEMBL6217340 | 0.87 | PPARG (0.38) | PPARGPTPN1SMN1; SMN2ALDH1A1PDE10A | |
| SCHEMBL6035983 | 0.87 | PPARG (0.48) | PPARGGAASCN9ANPC1EGLN1 | |
| SCHEMBL6034666 | 0.86 | PPARG (0.36) | PPARGPTPN1SMN1; SMN2ALDH1A1PDE10A | |
| SCHEMBL6215454 | 0.81 | PTPN1 (0.43) | PPARGGAAPTPN1ALDH1A1MCL1 | |
| SCHEMBL6221713 | 0.79 | KDM4E (0.31) | PPARGPTPN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL6215721 | 0.79 | PPARG (0.35) | PPARGPTPN1PDE10AMCL1 | |
| SCHEMBL6035698 | 0.78 | ABCB1 (0.38) | PPARGGAAALDH1A1MCL1 | |
| SCHEMBL6232363 | 0.78 | PPARG (0.33) | PPARGPTPN1PDE10AMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513817-A1 | 1, 2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Pharmaceutical Company Limited (JP) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003099793-A9 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL (JP) | 2005-02-10 | — | — | WO | disclosed |
| WO-2003099793-A1 | 1,2-AZOLE DERIVATIVES WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2003-12-04 | — | — | WO | disclosed |