Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 6/20 | 0.36 |
| ▸ | ACHE | P22303 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202429 | 0.87 | MAPK1 (0.42) | MAPK1RXFP1CSF1RBCHEACHE | |
| SCHEMBL28888309 | 0.84 | MEN1 (0.46) | NPSR1TOP2A | |
| SCHEMBL3867644 | 0.83 | RXFP1 (0.40) | MAPK1RXFP1CSF1RBCHEACHE | |
| SCHEMBL19475071 | 0.81 | TOP2A (0.41) | MAPK1RXFP1GAANPSR1CYP1A2 | |
| SCHEMBL3169059 | 0.81 | POLB (0.43) | MAPK1RXFP1CSF1RCYP1A2CYP3A4 | |
| SCHEMBL3861875 | 0.81 | CYP1A2 (0.42) | MAPK1RXFP1CSF1RBCHEACHE | |
| SCHEMBL4066480 | 0.81 | NPC1 (0.41) | BCHEACHEEGFRERBB2KDM4E | |
| SCHEMBL5319030 | 0.81 | MAPK1 (0.40) | MAPK1RXFP1CSF1RBCHEACHE | |
| SCHEMBL3861888 | 0.78 | MAPK1 (0.41) | MAPK1RXFP1CSF1RBCHEACHE | |
| SCHEMBL4524933 | 0.78 | ALDH1A1 (0.40) | MAPK1RXFP1GAANPSR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590348-A1 | ARYL / HETARYL SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2005-11-02 | — | — | EP | disclosed |
| WO-2004058759-A1 | ARYL / HETARYL SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-07-15 | — | — | WO | disclosed |