Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 5/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5880848 | 0.93 | GAA (0.34) | ALDH1A1SIGMAR1 | |
| SCHEMBL3993982 | 0.90 | RAB9A (0.38) | MEN1ALDH1A1KMT2A | |
| SCHEMBL3988758 | 0.86 | CTSC (0.41) | MMP12 | |
| SCHEMBL5880733 | 0.85 | RAB9A (0.33) | NAAA | |
| SCHEMBL5880732 | 0.85 | RAB9A (0.33) | NAAA | |
| SCHEMBL13964063 | 0.85 | RAB9A (0.33) | NAAAALDH1A1DRD2SIGMAR1 | |
| SCHEMBL13963704 | 0.85 | RAB9A (0.33) | MEN1ALDH1A1KMT2A | |
| SCHEMBL3986713 | 0.85 | GAA (0.33) | — | |
| SCHEMBL3993794 | 0.85 | CDK2 (0.34) | — | |
| SCHEMBL5880858 | 0.84 | RAB9A (0.35) | NAAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597246-A2 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004074270-A2 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2004-09-02 | — | — | WO | disclosed |