Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 7/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5468220 | 0.89 | KCNA3 (0.44) | ALDH1A1HPGDMEN1MAPK1KMT2A | |
| SCHEMBL6219970 | 0.83 | MEN1 (0.47) | ALDH1A1HPGDMEN1MAPK1KMT2A | |
| SCHEMBL3455507 | 0.81 | MEN1 (0.62) | ALDH1A1HPGDMEN1MAPK1KMT2A | |
| SCHEMBL5345113 | 0.76 | ALDH1A1 (0.41) | ALDH1A1HPGDMEN1MAPK1KMT2A | |
| SCHEMBL5353631 | 0.75 | KCNA3 (0.75) | ALDH1A1MEN1KMT2AKCNA3 | |
| SCHEMBL5353627 | 0.75 | KCNA3 (0.75) | ALDH1A1MEN1KMT2AKCNA3 | |
| SCHEMBL6221527 | 0.75 | ALDH1A1 (0.46) | ALDH1A1HPGDMEN1MAPK1KMT2A | |
| SCHEMBL5457922 | 0.74 | ALDH1A1 (0.45) | ALDH1A1HPGDMEN1MAPK1KMT2A | |
| SCHEMBL2857658 | 0.74 | KMT2A (0.55) | ALDH1A1HPGDMEN1MAPK1KMT2A | |
| SCHEMBL6220580 | 0.73 | ALDH1A1 (0.44) | ALDH1A1HPGDMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1507504-A1 | CYCLOALKYL INHIBITORS OF POTASSIUM CHANNEL FUNCTION | Bristol-Myers Squibb Company (US) | 2005-02-23 | — | — | EP | disclosed |
| WO-2003063797-A2 | CYCLOALKYL INHIBITORS OF POTASSIUM CHANNEL FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-08-07 | — | — | WO | disclosed |