Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 12/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 10/20 | 0.57 |
| ▸ | ICAM1 | P05362 | 10/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | GALK1 | P51570 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6219538 | 0.89 | ITGAL (0.49) | ITGALITGB2ICAM1RAB9ANPC1 | |
| SCHEMBL6220034 | 0.87 | SMN1; SMN2 (0.56) | ITGALITGB2ICAM1RAB9ANPC1 | |
| SCHEMBL6221157 | 0.87 | ITGAL (0.44) | ITGALITGB2ICAM1RAB9APOLB | |
| SCHEMBL6220626 | 0.86 | ITGAL (0.51) | ITGALITGB2ICAM1RAB9ANPC1 | |
| SCHEMBL6219181 | 0.84 | ITGAL (0.48) | ITGALITGB2ICAM1RAB9ANPC1 | |
| SCHEMBL6198410 | 0.84 | ITGAL (0.66) | ITGALITGB2ICAM1 | |
| SCHEMBL6197837 | 0.79 | ITGAL (0.57) | ITGALITGB2ICAM1RAB9ANPC1 | |
| SCHEMBL6217433 | 0.79 | HTT (0.56) | RAB9ANPC1SMN1; SMN2POLBMAPT | |
| SCHEMBL6220775 | 0.79 | TDP1 (0.40) | ITGALITGB2ICAM1MAPTKMT2A | |
| SCHEMBL6220724 | 0.76 | ITGAL (0.49) | ITGALITGB2ICAM1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140814-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2005-05-25 | — | — | EP | claimed |