Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6220034 | 0.90 | SMN1; SMN2 (0.56) | HTTALDH1A1MAPTGAAKDM4E | |
| SCHEMBL6218889 | 0.89 | HTT (0.52) | HTTALDH1A1MAPTGAACYP1A2 | |
| SCHEMBL6219538 | 0.88 | ITGAL (0.49) | HTTALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL6196634 | 0.87 | HTT (0.54) | HTTALDH1A1MAPTGAACYP1A2 | |
| SCHEMBL6199050 | 0.83 | HTT (0.51) | HTTALDH1A1MAPTGAACYP1A2 | |
| SCHEMBL6247601 | 0.81 | HTT (0.46) | HTTALDH1A1MAPTGAACYP1A2 | |
| SCHEMBL6220091 | 0.79 | ITGAL (0.57) | MAPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL6219332 | 0.79 | HTT (0.52) | HTTALDH1A1MAPTGAACYP1A2 | |
| SCHEMBL6221157 | 0.78 | ITGAL (0.44) | ALDH1A1MAPTHPGDRAB9APOLB | |
| SCHEMBL6222313 | 0.78 | ALDH1A1 (0.63) | HTTALDH1A1MAPTGAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140814-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2005-05-25 | — | — | EP | claimed |