Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LHCGR | P22888 | 3/20 | 0.57 |
| ▸ | BRAF | P15056 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 9/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6216225 | 0.89 | LHCGR (0.59) | LHCGRBRAFPDE4APDE4BPDE4C | |
| SCHEMBL6218448 | 0.88 | LHCGR (0.57) | LHCGRBRAFPDE4APDE4BPDE4C | |
| SCHEMBL6214088 | 0.86 | MAPT (0.60) | LHCGRBRAFPDE4APDE4BPDE4C | |
| SCHEMBL6216776 | 0.86 | LHCGR (0.58) | LHCGRBRAFPDE4APDE4BPDE4C | |
| SCHEMBL27475607 | 0.85 | MAPT (0.52) | LHCGRMAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL6217826 | 0.80 | LHCGR (0.54) | LHCGRBRAFPDE4APDE4BPDE4C | |
| SCHEMBL6215139 | 0.77 | LHCGR (0.59) | LHCGRMAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL4418734 | 0.77 | KDM4E (0.62) | BRAFPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27491950 | 0.76 | MAPT (0.48) | LHCGRBRAFPDE4APDE4BPDE4C | |
| SCHEMBL6219263 | 0.75 | MAPT (0.62) | LHCGRBRAFPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1171443-B1 | BICYCLIC HETEROAROMATIC COMPOUNDS USEFUL AS LH AGONISTS | AKZO NOBEL NV (NL) | 2005-07-13 | — | — | EP | disclosed |
| US-6841553-B2 | Bicyclic heteroaromatic compounds useful as LH agonists | AKZO NOBEL N.V. (NL) | 2005-01-11 | — | — | US | disclosed |
| US-20030212081-A1 | Bicyclic heteroaromatic compounds useful as LH agonists | MERCK SHARP & DOHME B.V. (NL) | 2003-11-13 | — | — | US | disclosed |
| US-6569863-B1 | Luteinizing hormone (LH) agonists for controlling fertility | AKZO NOBEL NV (NL) | 2003-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212081-A1 | Bicyclic heteroaromatic compounds useful as LH agonists | LHCGR, GNRHR, FSHR | LHCGR 1/4885BRAF 4753/4885PDE4A 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.