Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6218372 | 1.00 | KMT2A (0.44) | KMT2AMEN1ALDH1A1MAPK1MAPT | |
| SCHEMBL6219644 | 0.89 | KMT2A (0.46) | KMT2AMEN1ALDH1A1MAPK1MAPT | |
| SCHEMBL6219970 | 0.80 | MEN1 (0.47) | KMT2AMEN1ALDH1A1MAPK1MAPT | |
| SCHEMBL3455507 | 0.79 | MEN1 (0.62) | KMT2AMEN1ALDH1A1MAPK1RAB9A | |
| SCHEMBL6219965 | 0.78 | MEN1 (0.46) | KMT2AMEN1ALDH1A1MAPK1MAPT | |
| SCHEMBL6220388 | 0.75 | KMT2A (0.39) | KMT2AMEN1ALDH1A1MAPK1RAB9A | |
| SCHEMBL6218368 | 0.74 | MEN1 (0.43) | KMT2AMEN1ALDH1A1MAPK1MAPT | |
| SCHEMBL6220580 | 0.73 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1MAPK1RAB9A | |
| SCHEMBL6218371 | 0.73 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1MAPK1RAB9A | |
| SCHEMBL6220384 | 0.72 | MEN1 (0.39) | KMT2AMEN1ALDH1A1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1507504-A1 | CYCLOALKYL INHIBITORS OF POTASSIUM CHANNEL FUNCTION | Bristol-Myers Squibb Company (US) | 2005-02-23 | — | — | EP | disclosed |
| WO-2003063797-A2 | CYCLOALKYL INHIBITORS OF POTASSIUM CHANNEL FUNCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-08-07 | — | — | WO | disclosed |