Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | USP1 | O94782 | 1/20 | 0.39 |
| ▸ | USP19 | O94966 | 1/20 | 0.39 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5218987 | 0.75 | TARBP2 (0.42) | KDM4ELMNATARBP2PTPN2PTPN1 | |
| SCHEMBL6987242 | 0.75 | NPC1 (0.39) | KDM4ESLC9A1ALDH1A1NPSR1TSHR | |
| SCHEMBL5736248 | 0.74 | KDM4E (0.41) | KDM4ELMNATARBP2SLC9A1PTPN1 | |
| SCHEMBL6703700 | 0.73 | TARBP2 (0.46) | KDM4ELMNATARBP2PTPN1SMO | |
| SCHEMBL6220972 | 0.70 | KDM4E (0.54) | KDM4ELMNAPPARGPPARA | |
| SCHEMBL2520539 | 0.70 | FFAR1 (0.64) | KDM4EKDRTP53PPARGPPARA | |
| SCHEMBL6705288 | 0.70 | TARBP2 (0.39) | KDM4ELMNATARBP2PTPN1ALDH1A1 | |
| SCHEMBL6219926 | 0.70 | KDM4E (0.40) | KDM4ELMNATARBP2SLC9A1RCE1 | |
| SCHEMBL2089931 | 0.69 | KDM4E (0.56) | KDM4ETARBP2PTPN1USP1USP19 | |
| SCHEMBL28975550 | 0.68 | KDM4E (0.52) | KDM4ELMNAALDH1A1MAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597257-A1 | OXAZOLE-DERIVATIVES AS PPAR AGONISTS | PFIZER INC. (US) | 2005-11-23 | — | — | EP | disclosed |
| US-20040209929-A1 | Fused heteroaryl carboxylic acids as PPAR agonists | AGOURON PHARMACEUTICALS, INC. | 2004-10-21 | — | — | US | disclosed |
| WO-2004074284-A1 | OXAZOLE-DERIVATIVES AS PPAR AGONISTS | PFIZER INC. (US) | 2004-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209929-A1 | Fused heteroaryl carboxylic acids as PPAR agonists | PPARG, PPARA, PPARD | KDM4E 2860/4885LMNA 3569/4885TARBP2 2474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.