⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL62213 | 1.00 | — | — | |
| SCHEMBL822962 | 1.00 | — | — | |
| SCHEMBL11562125 | 0.80 | — | — | |
| SCHEMBL30880258 | 0.79 | HCAR2 (0.43) | — | |
| SCHEMBL23660467 | 0.78 | — | — | |
| SCHEMBL12572682 | 0.78 | — | — | |
| SCHEMBL3887611 | 0.78 | — | — | |
| SCHEMBL11620938 | 0.78 | — | — | |
| SCHEMBL21078445 | 0.78 | — | — | |
| SCHEMBL10821505 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119822981-A | Method for continuously synthesizing 3-methyl aminocrotonate | 新天地医药技术研究院(郑州)有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-119780272-A | Detection method of beta-methyl aminocrotonate | 浙江京新药业股份有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-115784962-B | Synthesis method of sunitinib pyrrole intermediate 2, 4-dimethylpyrrole-3-carboxylate | 华中科技大学 | 2025-04-04 | — | — | CN | claimed |
| CN-119735577-A | Amlodipine Process for the preparation of intermediates | 珠海润都制药股份有限公司 | 2025-04-01 | — | — | CN | claimed |
| CN-119708027-A | Method for preparing boronated carbonyl derivative | 中国科学院大连化学物理研究所 | 2025-03-28 | — | — | CN | claimed |
| US-20250066570-A1 | LAMINATE DEVICE WITH METALLIC AND POLYMER LAYERS | QUANTUM MICROMATERIALS INC (US) | 2025-02-27 | — | — | US | claimed |
| CN-118993993-A | Preparation method of benidipine nitrosamine impurity | 重庆圣华曦药业股份有限公司 | 2024-11-22 | — | — | CN | claimed |
| CN-118724738-A | Preparation method of high-purity horizon medicine | 乐声药业石家庄有限公司 | 2024-10-01 | — | — | CN | claimed |
| CN-117720457-A | Manidipine hydrochloride process impurity m-nifedipine and preparation method and application thereof | 成都大学 | 2024-03-19 | — | — | CN | claimed |
| CN-114149360-B | Preparation method of high-purity nitrendipine bulk drug | 天津太平洋化学制药有限公司 | 2024-03-01 | — | — | CN | claimed |
| EP-0160451-B1 | DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID ESTER DERIVATIVE ISOMERS, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-28 | — | — | EP | claimed |
| EP-0302980-B1 | 1,4-DIHYDROPYRIDINES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | LABORATORIOS DELAGRANGE S.A. (ES) | 1991-03-13 | — | — | EP | claimed |
| EP-0379351-A1 | 1,4-Dihydropyridine derivatives | SYNPHAR LABORATORIES INC. (CA) | 1990-07-25 | — | — | EP | claimed |
| US-4935516-A | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES, LTD. (JP) | 1990-06-19 | — | — | US | claimed |
| EP-0326389-A2 | Process for preparing 4-hydroxypyrimidine | UBE INDUSTRIES, LTD. (JP) | 1989-08-02 | — | — | EP | claimed |
| EP-0311053-A2 | Ameliorant of cerebral circulation and optical isomer of nb-818, processes for its production and its use | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-04-12 | — | — | EP | claimed |
| EP-0245680-A2 | A process for the preparation of 2-(N-benzyl-N-methylamino)-ethyl-methyl-1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine dicarboxylate hydrochloride | ISTITUTO LUSO FARMACO D'ITALIA S.p.A. (IT) | 1987-11-19 | — | — | EP | claimed |
| US-4552849-A | Method for determination of formaldehyde | KIKKOMAN CORPORATION (JP) | 1985-11-12 | — | — | US | claimed |
| EP-0160451-A2 | Dihydropyridine-3,5-dicarboxylic acid ester derivative isomers, their preparation, and pharmaceutical compositions containing them | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1985-11-06 | — | — | EP | claimed |
| US-4042646-A | BETA-AMINO-ALPHA, BETA-UNSATURATED KETONE, POLYESTERS | NIHON YUSHI CO., LTD. (JA) | 1977-08-16 | — | — | US | claimed |