Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14225485 | 0.84 | HCAR2 (0.53) | HCAR2KEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL15580368 | 0.80 | TDP1 (0.33) | ALOX15TDP1LMNABLMPMP22 | |
| SCHEMBL62213 | 0.79 | — | — | |
| SCHEMBL12923752 | 0.79 | HCAR2 (0.48) | HCAR2KEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL822962 | 0.79 | — | — | |
| SCHEMBL62212 | 0.79 | — | — | |
| SCHEMBL5953576 | 0.77 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL10769985 | 0.77 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL20930481 | 0.77 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL599553 | 0.77 | HCAR2 (0.46) | HCAR2KEAP1NFE2L2ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024089421-A1 | TETRAZOLE DERIVATIVES | SITRYX THERAPEUTICS LIMITED (GB) | 2024-05-02 | — | — | WO | disclosed |