Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.44 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | SNCA | P37840 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6221716 | 0.93 | PDE4A (0.47) | CNR1CNR2PDE4APDE4BPDE4C | |
| SCHEMBL6221877 | 0.86 | PDE4A (0.47) | CNR1CNR2PDE4APDE4BPDE4C | |
| SCHEMBL6224031 | 0.86 | CNR1 (0.42) | CNR1CNR2PDE4APDE4BPDE4C | |
| SCHEMBL6223092 | 0.86 | PDE4A (0.46) | CNR1CNR2PDE4APDE4BPDE4C | |
| SCHEMBL6224864 | 0.85 | PDE4A (0.57) | CNR1CNR2PDE4APDE4BPDE4C | |
| SCHEMBL6224573 | 0.83 | PDE4A (0.44) | CNR1CNR2PDE4APDE4BPDE4C | |
| SCHEMBL6222086 | 0.83 | PDE4A (0.44) | CNR1CNR2PDE4APDE4BPDE4C | |
| SCHEMBL6223444 | 0.80 | PDE4A (0.44) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL6222256 | 0.80 | PDE4A (0.41) | CNR1CNR2PDE4APDE4BPDE4C | |
| SCHEMBL6222412 | 0.78 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330455-B1 | NOVEL 7-AZAINDOLES, USE THEREOF AS PHOSPHODIESTERASE 4 INHIBITORS AND METHOD FOR PRODUCING THE SAME | ELBION AG (DE) | 2005-08-03 | — | — | EP | claimed |