Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6222754 | 0.91 | PDE4A (0.49) | CNR1CNR2PDE4APDE4BPDE4C | |
| SCHEMBL6221716 | 0.87 | PDE4A (0.47) | CNR1CNR2PDE4APDE4BPDE4C | |
| SCHEMBL6221652 | 0.86 | CNR1 (0.44) | CNR1CNR2PDE4APDE4BPDE4C | |
| SCHEMBL6223092 | 0.84 | PDE4A (0.46) | CNR1CNR2PDE4APDE4BPDE4C | |
| SCHEMBL6223621 | 0.81 | TP53 (0.45) | CNR1CNR2PDE4APDE4BPDE4C | |
| SCHEMBL6221877 | 0.80 | PDE4A (0.47) | CNR1CNR2PDE4APDE4BPDE4C | |
| SCHEMBL6224864 | 0.80 | PDE4A (0.57) | CNR1CNR2PDE4APDE4BPDE4C | |
| SCHEMBL6222086 | 0.78 | PDE4A (0.44) | CNR1CNR2PDE4APDE4BPDE4C | |
| SCHEMBL6226018 | 0.77 | TSHR (0.43) | CNR1CNR2PDE4APDE4BPDE4C | |
| SCHEMBL6224573 | 0.76 | PDE4A (0.44) | CNR1CNR2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330455-B1 | NOVEL 7-AZAINDOLES, USE THEREOF AS PHOSPHODIESTERASE 4 INHIBITORS AND METHOD FOR PRODUCING THE SAME | ELBION AG (DE) | 2005-08-03 | — | — | EP | claimed |