⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20591004 | 0.87 | TDP1 (0.32) | — | |
| SCHEMBL2985387 | 0.85 | — | — | |
| SCHEMBL1204722 | 0.78 | — | — | |
| SCHEMBL27141 | 0.73 | — | — | |
| SCHEMBL6755152 | 0.69 | — | — | |
| SCHEMBL3042853 | 0.67 | — | — | |
| SCHEMBL27590107 | 0.65 | — | — | |
| SCHEMBL28700649 | 0.65 | CA1 (0.42) | — | |
| SCHEMBL180320 | 0.62 | TSHR (0.32) | — | |
| SCHEMBL8537271 | 0.62 | TSHR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 287 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230049719-A1 | PYRAZOLO[3,4-B]PYRAZINE SHP2 PHOSPHATASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-02-16 | — | — | US | claimed |
| US-11561175-B2 | Detection of hydrocarbon contamination in soil and water | Bundesrepublik Deutschland, vertreten durch die Bundesministerin für Wirtschaft und Energie, diese vertreten durch den Präsidenten der Bundesanstalt für Materialforgchung und- Prüfung (BAM) (DE) | 2023-01-24 | — | — | US | claimed |
| CN-114874244-A | Preparation method of arylboronic acid ester or alkyl boronate compound | 中国科学院兰州化学物理研究所 | 2022-08-09 | — | — | CN | claimed |
| EP-4017855-A1 | PYRAZOLO[3,4-B]PYRAZINE SHP2 PHOSPHATASE INHIBITORS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2022-06-29 | — | — | EP | claimed |
| US-20210107908-A1 | PHARMACEUTICAL COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-04-15 | — | — | US | claimed |
| WO-2021033153-A1 | PYRAZOLO[3,4-B]PYRAZINE SHP2 PHOSPHATASE INHIBITORS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-02-25 | — | — | WO | claimed |
| EP-3759111-A1 | PHARMACEUTICAL COMPOUNDS | Otsuka Pharmaceutical Co., Ltd. (JP) | 2021-01-06 | — | — | EP | claimed |
| EP-3688457-A1 | DETECTION OF HYDROCARBON CONTAMINATION IN SOIL AND WATER | Bundesrepublik Deutschland, vertreten durch das Bundesministerium für Wirtschaft und Technologie, Dieses vertreten durch den Präsidenten der BAM, (DE) | 2020-08-05 | — | — | EP | claimed |
| US-20200232918-A1 | DETECTION OF HYDROCARBON CONTAMINATION IN SOIL AND WATER | Bundesrepublik Deutschland, vertreten durch die Bundesministerin für Wirtschaft und Energie (DE) | 2020-07-23 | — | — | US | claimed |
| WO-2019063100-A1 | DETECTION OF HYDROCARBON CONTAMINATION IN SOIL AND WATER | BUNDESREPUBLIK DEUTSCHLAND, VERTRETEN DURCH DIE BUNDESMINISTERIN FÜR WIRTSCHAFT UND ENERGIE, DIESE VERTRETEN DURCH DEN PRÄSIDENTEN DER BUNDESANSTALT FÜR MATERIALFORSCHUNG UND -PRÜFUNG (BAM) (DE) | 2019-04-04 | — | — | WO | claimed |
| WO-2005028474-A2 | PYRAZOLOQUINOLINE DERIVATIVES AS CHK-1 INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2005-03-31 | — | — | WO | claimed |
| EP-1499662-A1 | PREPATION OF A CONJUGATED MOLECULE AND MATERIALS FOR USE THEREIN | Avecia Limited (GB) | 2005-01-26 | — | — | EP | claimed |
| WO-2003089499-A1 | PREPATION OF A CONJUGATED MOLECULE AND MATERIALS FOR USE THEREIN | AVECIA LIMITED (GB) | 2003-10-30 | — | — | WO | claimed |
| US-20030096989-A1 | Refined routes to chlorin building blocks | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2003-05-22 | — | — | US | claimed |
| US-6559374-B2 | Multilayer solar cells | NORTH CAROLINA STATE UNIVERSITY | 2003-05-06 | — | — | US | claimed |
| WO-2002092601-A1 | REFINED ROUTES TO CHLORIN BUILDING BLOCKS | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-11-21 | — | — | WO | claimed |
| US-20020033192-A1 | Trans beta substituted chlorins and methods of making and using the same | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2002-03-21 | — | — | US | claimed |
| WO-2002008230-A1 | TRANS BETA SUBSTITUTED CHLORINS AND METHODS OF MAKING AND USING THE SAME | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-01-31 | — | — | WO | claimed |
| WO-1995013284-A1 | ASYMMETRIC HYDROBORATION | ISIS INNOVATION LIMITED (GB) | 1995-05-18 | — | — | WO | claimed |
| US-4772751-A | EASILY SEPARATED FROM BY-PRODUCTS | ALDRICH-BORANES, INC. (US) | 1988-09-20 | — | — | US | claimed |