SCHEMBL622225

SCHEMBL622225

CCc1cccc(C(=O)O)c1C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLCN2 P51788 1/20 0.54
TSHR P16473 1/20 0.50
MRGPRX4 Q96LA9 1/20 0.50
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 2/20 0.48
HSD17B10 Q99714 2/20 0.48
HPGD P15428 1/20 0.48
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
ALOX15 P16050 1/20 0.46
HMGB1 P09429 1/20 0.46
FOLH1 Q04609 1/20 0.46
HTT P42858 1/20 0.45
MYC P01106 2/20 0.44
TDP1 Q9NUW8 2/20 0.43
MEN1 O00255 1/20 0.43
AKR1B10 O60218 1/20 0.43
TRPA1 O75762 1/20 0.43
ABCB11 O95342 1/20 0.43
DHFR P00374 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28861692 1.00 CLCN2 (0.54) CLCN2TSHRMRGPRX4ALDH1A1KDM4E
SCHEMBL2362450 0.86 MRGPRX4 (0.47) CLCN2TSHRMRGPRX4ALDH1A1KDM4E
SCHEMBL2652419 0.86 PDCD1 (0.53) CLCN2TSHRMRGPRX4ALDH1A1KDM4E
SCHEMBL28708772 0.85 GABRA1 (0.48) CLCN2TSHRMRGPRX4ALDH1A1HSD17B10
SCHEMBL8179315 0.84 AKR1B1 (0.48) CLCN2TSHRMRGPRX4ALDH1A1KDM4E
SCHEMBL15206277 0.84 MRGPRX4 (0.48) CLCN2TSHRMRGPRX4ALDH1A1KDM4E
SCHEMBL6617739 0.84 MRGPRX4 (0.51) CLCN2TSHRMRGPRX4ALDH1A1KDM4E
SCHEMBL18049144 0.84 HMGB1 (0.51) CLCN2TSHRMRGPRX4ALDH1A1KDM4E
SCHEMBL7963839 0.84 FOLH1 (0.52) CLCN2TSHRMRGPRX4ALDH1A1KDM4E
SCHEMBL19748199 0.84 MRGPRX4 (0.48) CLCN2TSHRMRGPRX4ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 295 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119301224-A 2-Methylbenzoic acid ethyl ester as perfume 西姆莱斯股份公司 2025-01-10 CN claimed
CN-117486712-A Flash separation process of m-methylbenzoic acid 常州大学 2024-02-02 CN claimed
US-8569195-B2 Internal and external donor compounds for olefin polymerization catalysts II BASF CORPORATION (US) 2013-10-29 US claimed
EP-2539375-A2 INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II BASF Corporation (US) 2013-01-02 EP claimed
WO-2011106480-A2 INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II BASF CORPORATION (US) 2011-09-01 WO claimed
US-20110207901-A1 INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS II BASF CATALYSTS LLC (US) 2011-08-25 US claimed
JP-5186646-A None JP disclosed
CN-119301224-A 2-Methylbenzoic acid ethyl ester as perfume 西姆莱斯股份公司 2025-01-10 CN disclosed
CN-117530943-A Formulations for administration of efluromithine 奥巴斯治疗股份有限公司 2024-02-09 CN disclosed
US-11834456-B2 11,13-modified saxitoxins for the treatment of pain SITEONE THERAPEUTICS, INC. (US) 2023-12-05 US disclosed
CN-111164084-B Triazolotriazine derivatives useful as A2A receptor antagonists 浙江春禾医药科技有限公司 2023-05-23 CN disclosed
CN-116139138-A Heterocyclic modulators of lipid synthesis 3-V生物科学股份有限公司 2023-05-23 CN disclosed
CN-115210221-A Isoxazoline derivatives as pesticides 礼蓝动物保健有限公司 2022-10-18 CN disclosed
EP-0736552-A2 Propylene homopolymer AMOCO CORPORATION (US) 1996-10-09 EP disclosed
US-5430023-A Tripeptide antithrombotic agents ELI LILLY AND COMPANY (US) 1995-07-04 US disclosed
JP-H05186646-A POLYPROPYLENE-BASED RESIN COMPOSITION TOSOH CORP 1993-07-27 JP disclosed
US-5218052-A Increased stiffness and broadend molecular weight distribution AMOCO CORPORATION (US) 1993-06-08 US disclosed
EP-0507576-A1 Polypropylene-based resin compositions TOSOH CORPORATION (JP) 1992-10-07 EP disclosed
EP-0498603-A2 Olefin polymerization and copolymerization process AMOCO CORPORATION (US) 1992-08-12 EP disclosed
US-4467115-A Method for preparing branched polyethylenimine INSTITUT NEFTEKHIMICHESKOGO SINTEZA IMENI A.V. TONCHEVA AKADEMII NAUK SSSR (SU) 1984-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834456-B2 11,13-modified saxitoxins for the treatment of pain SCN11A, SCN10A, CACNA1A CLCN2 372/4885TSHR 2253/4885MRGPRX4 208/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.