Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27758268 | 0.83 | HPGD (0.62) | HPGDL3MBTL1ATMTDP1KMT2A | |
| SCHEMBL19625794 | 0.81 | HPGD (0.55) | HPGDL3MBTL1ATMTDP1ALDH1A1 | |
| SCHEMBL16695405 | 0.80 | KMT2A (0.67) | HPGDL3MBTL1ATMTDP1KMT2A | |
| SCHEMBL23966960 | 0.78 | BRD4 (0.59) | HPGDL3MBTL1BRD4ALDH1A1MAPK1 | |
| SCHEMBL12345122 | 0.77 | ALDH1A1 (0.55) | KMT2AALDH1A1TSHR | |
| SCHEMBL795756 | 0.77 | HPGD (0.54) | HPGDL3MBTL1ATMTDP1KMT2A | |
| SCHEMBL12667142 | 0.77 | BRD4 (0.67) | HPGDL3MBTL1BRD4KMT2AALDH1A1 | |
| SCHEMBL28956225 | 0.77 | BRD4 (0.67) | HPGDL3MBTL1BRD4KMT2AALDH1A1 | |
| SCHEMBL30282498 | 0.77 | BRD4 (0.67) | HPGDL3MBTL1BRD4KMT2AALDH1A1 | |
| SCHEMBL27047902 | 0.77 | HPGD (0.52) | HPGDL3MBTL1ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104402791-A | Preparation method for nebracetam | UNIV HENAN NORMAL | 2015-03-11 | — | — | CN | disclosed |
| EP-1537106-A1 | DIHYDROPYRAZOLOPYRIDINE COMPOUNDS | Mitsubishi Pharma Corporation (JP) | 2005-06-08 | — | — | EP | disclosed |
| WO-2004014910-A1 | DIHYDROPYRAZOLOPYRIDINE COMPOUNDS | MITSUBISHI PHARMA CORPORATION (JP) | 2004-02-19 | — | — | WO | disclosed |