Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 7/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6221361 | 0.98 | KCNH2 (0.40) | SLC2A1KCNH2 | |
| Oxalic Acid SCHEMBL7831830 | 0.89 | SLC2A1 (0.39) | SLC2A1KCNH2 | |
| Oxalic Acid SCHEMBL6224062 | 0.88 | SLC2A1 (0.38) | SLC2A1KCNH2CHRM3 | |
| Oxalic Acid SCHEMBL6222717 | 0.85 | CCR8 (0.48) | SLC2A1KCNH2 | |
| Oxalic Acid SCHEMBL6222719 | 0.85 | CCR8 (0.48) | SLC2A1KCNH2 | |
| SCHEMBL6224107 | 0.82 | CCR8 (0.49) | SLC2A1KCNH2 | |
| SCHEMBL6224110 | 0.82 | CCR8 (0.49) | SLC2A1KCNH2 | |
| SCHEMBL6224111 | 0.82 | CCR8 (0.49) | SLC2A1KCNH2 | |
| Oxalic Acid SCHEMBL6215855 | 0.81 | SLC2A1 (0.40) | SLC2A1KCNH2 | |
| SCHEMBL6218218 | 0.81 | SLC2A1 (0.39) | SLC2A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121355-B1 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2005-12-14 | — | — | EP | disclosed |
| US-6602882-B1 | Quinoline derivatives and their use as antibacterial agents | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-08-05 | — | — | US | disclosed |
| EP-1121355-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2001-08-08 | — | — | EP | disclosed |
| WO-2000021952-A1 | QUINOLINE DERIVATIVES AND THEIR USE AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2000-04-20 | — | — | WO | disclosed |