SCHEMBL6223243

SCHEMBL6223243

CCCCCCOc1ccccc1[C]=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
NR1I2 O75469 1/20 0.54
CHRM2 P08172 1/20 0.54
CYP3A4 P08684 1/20 0.54
ADRA2A P08913 1/20 0.54
MAPT P10636 1/20 0.54
OPRK1 P41145 1/20 0.54
HTR2B P41595 1/20 0.54
SLC6A3 Q01959 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
ALDH1A1 P00352 2/20 0.48
HPGD P15428 1/20 0.48
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
CYSLTR2 Q9NS75 2/20 0.44
CYSLTR1 Q9Y271 2/20 0.44
TSHR P16473 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2121443 1.00 LMNA (0.54) LMNAMEN1KMT2ANR1I2CHRM2
SCHEMBL2118989 1.00 LMNA (0.54) LMNAMEN1KMT2ANR1I2CHRM2
SCHEMBL473968 1.00 LMNA (0.54) LMNAMEN1KMT2ANR1I2CHRM2
SCHEMBL2123796 1.00 LMNA (0.54) LMNAMEN1KMT2ANR1I2CHRM2
SCHEMBL2121850 1.00 LMNA (0.54) LMNAMEN1KMT2ANR1I2CHRM2
SCHEMBL7830925 1.00 LMNA (0.54) LMNAMEN1KMT2ANR1I2CHRM2
SCHEMBL2121240 1.00 LMNA (0.54) LMNAMEN1KMT2ANR1I2CHRM2
SCHEMBL8453578 1.00 LMNA (0.54) LMNAMEN1KMT2ANR1I2CHRM2
SCHEMBL2244225 0.98 CYP3A4 (0.51) LMNAMEN1KMT2ANR1I2CHRM2
SCHEMBL195415 0.93 CYP1A2 (0.55) LMNAMEN1KMT2ANR1I2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0755434-B1 DETERGENTS CONTAINING A BUILDER AND A DELAYED RELEASE ENZYME PROCTER & GAMBLE (US) 2005-03-16 EP disclosed
US-6559113-B2 Water-soluble builder and an enzyme, wherein a means is provided for delaying the release to the wash solution of said enzyme relative to the release of said water-soluble builder THE PROCTER & GAMBLE COMPANY 2003-05-06 US disclosed
US-20030064907-A1 DETERGENTS CONTAINING A BUILDER AND A DELAYED RELEASED ENZYME PROCTER & GAMBLE COMPANY, THE 2003-04-03 US disclosed
EP-0714898-B1 PYRAZOLO [1,5-a]PYRIMIDINE DERIVATIVE OTSUKA PHARMA CO LTD (JP) 2001-11-14 EP disclosed
US-6313086-B1 GRANULAR DETERGENT COMPOSITION COMPRISING SULFATE SALT, ACID DISPERSING AID AND ALKALI SOURCE, WHICH HAVE SPECIFIED PARTICLE SIZE AND ARE CAPABLE OF REACTING TOGETHER IN PRESENCE OF WATER TO PRODUCE GAS THE PROCTER & GAMBLE COMPANY 2001-11-06 US disclosed
EP-1141200-A1 DETERGENT COMPOSITIONS COMPRISING A PECTATE LYASE AND A BLEACH SYSTEM THE PROCTER & GAMBLE COMPANY (US) 2001-10-10 EP disclosed
EP-0706559-B1 MACHINE DISHWASHING COMPOSITION CONTAINING OXYGEN BLEACH AND PARAFFIN OIL AND BENZOTRIAZOLE COMPOUND SILVER TARNISHING INHIBITORS PROCTER & GAMBLE (US) 2001-08-08 EP disclosed
WO-2000042156-A9 DETERGENT COMPOSITIONS COMPRISING A PECTATE LYASE AND A BLEACH SYSTEM PROCTER & GAMBLE (US) 2001-06-28 WO disclosed
US-6221430-B1 SPRAYING AN AQUEOUS BINDER MIXTURE; DRYING THE PROCTER & GAMBLE COMPANY 2001-04-24 US disclosed
WO-2000042156-A1 DETERGENT COMPOSITIONS COMPRISING A PECTATE LYASE AND A BLEACH SYSTEM THE PROCTER & GAMBLE COMPANY (US) 2000-07-20 WO disclosed
US-5405413-A Peroxygen bleaching compounds THE PROCTER & GAMBLE CO. (US) 1995-04-11 US disclosed
WO-1995001416-A1 MACHINE DISHWASHING COMPOSITION CONTAINING OXYGEN BLEACH AND PARAFFIN OIL AND BENZOTRIAZOLE COMPOUND SILVER TARNISHING INHIBITORS THE PROCTER & GAMBLE COMPANY (US) 1995-01-12 WO disclosed
WO-1995000626-A1 BLEACHING COMPOUNDS COMPRISING ACYL VALEROLACTAM BLEACH ACTIVATORS THE PROCTER & GAMBLE COMPANY (US) 1995-01-05 WO disclosed
US-5306719-A Cardiotonic agents OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-04-26 US disclosed
EP-0255134-B1 CARBOSTYRIL DERIVATIVES AND SALTS THEREOF, PROCESS FOR PREPARING THEM, AND CARDIOTONIC COMPOSITION CONTAINING SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-03-03 EP disclosed
US-5162305-A Calcium lowering in blood; hypoglycemic agents, analgesics OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-11-10 US disclosed
US-5071856-A CARBOSTYRIL DERIVATIVES AND SALTS THEREOF OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-12-10 US disclosed
US-4886809-A CARDIOTONIC AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-12-12 US disclosed
CN-1036582-A The preparation method of polypeptide derivative OTSUKA CHEMICAL CO LTD (JP) 1989-10-25 CN disclosed
EP-0330241-A2 Calcitonin derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-08-30 EP disclosed