Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MC4R | P32245 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 1/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28508256 | 0.82 | KDM4E (0.39) | ALDH1A1MAPK1CYP3A4BLMCHRM2 | |
| SCHEMBL10937561 | 0.81 | ALDH1A1 (0.34) | CYP2C19ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL16425174 | 0.81 | KDM4E (0.42) | CYP2C19ALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL11834190 | 0.77 | TDP1 (0.34) | CYP2C19ALDH1A1LMNAMAPK1CYP3A4 | |
| SCHEMBL2835194 | 0.75 | ALDH1A1 (0.49) | CYP2C19CYP2D6ALDH1A1LMNAMAPK1 | |
| SCHEMBL13097913 | 0.75 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTMAPK1CYP3A4 | |
| SCHEMBL17758492 | 0.75 | EPHX1 (0.43) | CYP2D6ALDH1A1MAPTCYP3A4GAA | |
| SCHEMBL17758474 | 0.75 | HSD17B10 (0.34) | CYP2C19ALDH1A1LMNAMAPK1CHRM2 | |
| SCHEMBL13097915 | 0.73 | ALDH1A1 (0.38) | ALDH1A1LMNAMAPTMAPK1CYP3A4 | |
| SCHEMBL13594990 | 0.73 | CNR2 (0.36) | CYP2C19CYP2D6ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558612-A1 | IMIDAZOPYRIDINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004043957-A1 | IMIDAZOPYRIDINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2004-05-27 | — | — | WO | disclosed |