Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 6/20 | 0.35 |
| ▸ | CNR2 | P34972 | 3/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6224761 | 0.98 | POLB (0.42) | POLBLMNAL3MBTL1KMT2AGRIN2B | |
| SCHEMBL3004953 | 0.94 | KMT2A (0.36) | POLBKMT2AHRH4HRH3CCRL2 | |
| SCHEMBL3002040 | 0.92 | POLB (0.37) | POLBLMNAL3MBTL1KMT2AHRH4 | |
| SCHEMBL2996174 | 0.91 | CNR1 (0.34) | POLBKMT2AHRH4HRH3CCRL2 | |
| SCHEMBL6223373 | 0.89 | BACE1 (0.38) | POLBLMNAL3MBTL1KMT2AGRIN2B | |
| SCHEMBL4141004 | 0.88 | CNR1 (0.34) | KMT2ACNR1CNR2EGFR | |
| SCHEMBL6226058 | 0.86 | HRH4 (0.41) | HRH4HRH3CNR1CNR2EGFR | |
| SCHEMBL6226694 | 0.85 | HRH4 (0.37) | LMNAL3MBTL1GRIN2BHRH4HRH3 | |
| SCHEMBL3000705 | 0.85 | EGFR (0.33) | HRH4HRH3CCRL2CNR1CNR2 | |
| SCHEMBL2997119 | 0.84 | ALDH1A1 (0.35) | LMNAKMT2AHRH4HRH3CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1583757-A1 | NOVEL SUBSTITUTED NITROGEN-CONTAINING HETEROBICYCLES AND USE THEREOF AS FACTOR XA INHIBITORS | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2005-10-12 | — | — | EP | disclosed |
| WO-2004058743-A1 | NOVEL SUBSTITUTED NITROGEN-CONTAINING HETEROBICYCLES AND USE THEREOF AS FACTOR XA INHIBITORS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-07-15 | — | — | WO | disclosed |