Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL777525 | 0.77 | SMN1; SMN2 (0.34) | LMNASMN1; SMN2HTTCA1TSHR | |
| SCHEMBL6012003 | 0.74 | LMNA (0.33) | LMNASMN1; SMN2HTTCA1NPC1 | |
| SCHEMBL12256296 | 0.74 | LMNA (0.33) | LMNASMN1; SMN2HTTCA1NPC1 | |
| SCHEMBL6224354 | 0.74 | SMN1; SMN2 (0.33) | LMNASMN1; SMN2HTTCA1NPC1 | |
| SCHEMBL381097 | 0.67 | CA1 (0.56) | LMNASMN1; SMN2HTTCA1TSHR | |
| SCHEMBL667530 | 0.67 | CA1 (0.47) | LMNASMN1; SMN2HTTCA1TSHR | |
| SCHEMBL2880721 | 0.67 | CA1 (0.38) | LMNASMN1; SMN2HTTCA1TSHR | |
| SCHEMBL6662522 | 0.66 | — | — | |
| SCHEMBL27879460 | 0.66 | CA1 (0.32) | SMN1; SMN2CA1TSHRCA12CA2 | |
| SCHEMBL244840 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599465-A1 | SUBSTITUTED N-ARYL NITROGEN HETEROCYCLES | Bayer CropScience AG (DE) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004074274-A1 | SUBSTITUTED N-ARYL NITROGEN HETEROCYCLES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-09-02 | — | — | WO | disclosed |