Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 11/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4341723 | 0.89 | MAPT (0.49) | SMN1; SMN2THRBMAPTKDM4EMEN1 | |
| SCHEMBL6224490 | 0.86 | MAPT (0.44) | SMN1; SMN2THRBMAPTKDM4EMEN1 | |
| SCHEMBL12846511 | 0.85 | SMN1; SMN2 (0.49) | SMN1; SMN2THRBMAPTKDM4EMEN1 | |
| SCHEMBL4354538 | 0.80 | SMN1; SMN2 (0.52) | SMN1; SMN2THRBMAPTKDM4EMEN1 | |
| SCHEMBL4352804 | 0.77 | MAPT (0.56) | SMN1; SMN2THRBMAPTKDM4EMEN1 | |
| SCHEMBL4347962 | 0.74 | MAPT (0.48) | SMN1; SMN2THRBMAPTKDM4EMEN1 | |
| SCHEMBL4344552 | 0.74 | NAMPT (0.57) | SMN1; SMN2THRBMAPTKDM4EMEN1 | |
| SCHEMBL12846756 | 0.74 | TP53 (0.49) | SMN1; SMN2THRBMAPTKDM4EMEN1 | |
| SCHEMBL4347124 | 0.72 | EPHX2 (0.48) | SMN1; SMN2THRBMAPTKDM4EMEN1 | |
| SCHEMBL4561504 | 0.72 | MAPT (0.54) | SMN1; SMN2THRBMAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539683-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | Jerini AG (DE) | 2005-06-15 | — | — | EP | claimed |
| WO-2004030664-A2 | NEW COMPOUNDS FOR THE INHIBITION OF UNDESIRED CELL PROLIFERATION AND USE THEREOF | JERINI AG (DE) | 2004-04-15 | — | — | WO | claimed |
| WO-2004026815-A2 | PHENOL DERIVATIVES AND THEIR USE AS ROTAMASE INHIBITORS | JERINI AG (DE) | 2004-04-01 | — | — | WO | claimed |